Ion channels

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Equivalent Gain-of-Function Variants in KCNK3 and KCNK9 and their Contribution to Distinct TASK K2P Channelopathies

Authors:

Kate M Crowther, Thibault RH Jouen-Tachoire, Peter Proks, Peter Rory Hall, Emma L Veale, Janina Sörmann, Karin EJ Rödström, Thomas Müller, Saskia B Wortmann, Nina Barisic, Natalie Hauser, Vincenzo Salpietro Damiano, RaeLynn Forsyth, Linford Williams, Carlos A Bacino, Jill A Rosenfeld, Henry Houlden, Simon Newstead, Caroline F Wright, James Fasham, Alistair A Mathie, Reza Maroofian, Stephen J Tucker
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Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation

Authors:

Karin EJ Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn HM Smith, Ashley CW Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
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Induced Polarization in MD Simulations of the 5HT3 Receptor Channel

Cold Spring Harbor Laboratory 2020.03.01.971853

Authors:

Gianni Klesse, Shanlin Rao, Stephen J Tucker, Mark SP Sansom
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Influence of Electronic Polarization on the Binding of Anions to a Chloride-Pumping Rhodopsin

Authors:

Linda X Phan, Victor Cruces Chamorro, Hector Martinez-Seara, Jason Crain, Mark SP Sansom, Stephen J Tucker
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Influence of effective polarization on ion and water interactions within a biomimetic nanopore

Authors:

Linda X Phan, Charlotte I Lynch, Jason Crain, Mark SP Sansom, Stephen J Tucker
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