LHCb

Abstract:

Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enrolled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.85-1.46; p=0.42). There was no significant effect of DMF on any secondary outcome.

Abstract:

Based on e+e− collision data collected at center-of-mass energies from 2.000 to 3.080 GeV by the BESIII detector at the BEPCII collider, a partial wave analysis is performed for the process e+e− → KS0KL0π0. The results allow the Born cross sections of the process e+e− → KS0KL0π0, as well as its subprocesses e+e− → K∗(892)0K¯0 and K2∗(1430)0K¯0 to be measured. The Born cross sections for e+e− → KS0KL0π0 are consistent with previous measurements by BaBar, but with substantially improved precision. The Born cross section lineshape of the process e+e−K∗(892)0K¯0 is consistent with a vector meson state around 2.2 GeV with a significance of 3.2σ. A Breit-Wigner fit determines its mass as MY = (2164.7 ± 9.1 ± 3.1) MeV/c2 and its width as ΓY = (32.4 ± 21.0 ± 1.8) MeV.

Abstract:

Using (10087 ± 44) × 106J/ψ events collected with the BESIII detector at the BEPCII e+e− storage ring at the center-of-mass energy of s = 3.097 GeV, we present a search for the rare semi-muonic charmonium decay J/ψ → D−μ+νμ + c.c.. Since no significant signal is observed, we set an upper limit of the branching fraction to be B (J/ψ → D−μ+νμ + c.c.) < 5.6 × 10−7 at 90% confidence level. This is the first search for the weak decay of charmonium with a muon in the final state.