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DNA tetrahedron

Professor Andrew Turberfield

Professor of Biological Physics

Research theme

  • Biological physics

Sub department

  • Condensed Matter Physics

Research groups

  • Nucleic acid nanotechnology
Andrew.Turberfield@physics.ox.ac.uk
  • About
  • Publications

We work with synthetic biomolecular nanostructures built by self-assembly. Nucleic acid nanostructures are atomically precise and dynamically reconfigurable: by designing synthetic strands of DNA or RNA we can create autonomous molecular systems that sense, compute and actuate. We are developing the physics and technology of functional nucleic acid nanostructures to create disruptive technologies, including templates for molecular electronics and molecular machinery for atomically precise manufacture and chemical discovery. We are also working on probes of cellular structure and function.

Research interests

Biophysics
Self-assembly
Nanotechnology
Molecular Machinery

Selected publications

DNA origami signposts for identifying proteins on cell membranes by electron cryotomography

Cell Cell Press 184:4 (2021) 1110-1121.e16
Emma Silvester, Benjamin Vollmer, Vojtěch Pražák, Daven Vasishtan, Emily A Machala, Catheryne Whittle, Susan Black, Jonathan Bath, Andrew J Turberfield, Kay Grünewald, Lindsay A Baker

Strategies for constructing and operating DNA origami linear actuators

Small Wiley 17:20 (2021) 2007704
Erik Benson, Rafael Carrascosa Marzo, Jonathan Bath, Andrew Turberfield

Design of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during DNA strand displacement

Nature Communications Springer Nature 11 (2020) 2562
Natalie EC Haley, Thomas E Ouldridge, Ismael Mullor Ruiz, Alessandro Geraldini, Adriaan Louis, Jonathan Bath, Andrew J Turberfield

Reconfigurable T‐junction DNA origami

Angewandte Chemie Wiley (2020) ange.202006281
Katherine Young, Behnam Najafi, William Sant, Sonia Contera, Ard Louis, Jonathan Doye, Andrew Turberfield, Jonathan Bath
158431 48698 158429
See all publications

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