Gene expression is the vital path that converts DNA information into functional proteins. Our group studies mechanisms and machines of gene expression using single-molecule biophysical methods and biochemistry. We observe single biomachines in real time, both "in vitro" and inside living cells. We also develop single-molecule fluorescence methods, instruments, assays and DNA-based biosensors.
Our lab is based at the Kavli Institute for Nanoscience Discovery.
Research interests
Single-molecule Biophysics
Protein machines of gene expression
Single-molecule imaging
Genetic mechanisms of bacteria and viruses