Learning Influential Genes on Cancer Gene Expression Data with Stacked Denoising Autoencoders
Institute of Electrical and Electronics Engineers (IEEE) (2017) 1201-1205
Co-expression networks reveal the tissue-specific regulation of transcription and splicing
Genome Research Cold Spring Harbor Laboratory 27:11 (2017) 1843-1858
Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis
Genome Research Cold Spring Harbor Laboratory 27:11 (2017) 1859-1871
KiDS-450 + 2dFLenS: Cosmological parameter constraints from weak gravitational lensing tomography and overlapping redshift-space galaxy clustering
Monthly Notices of the Royal Astronomical Society Oxford University Press 474:4 (2017) 4894-4924
Abstract:
We perform a combined analysis of cosmic shear tomography, galaxy-galaxy lensing tomography, and redshift-space multipole power spectra (monopole and quadrupole) using 450 deg$^2$ of imaging data by the Kilo Degree Survey (KiDS) overlapping with two spectroscopic surveys: the 2-degree Field Lensing Survey (2dFLenS) and the Baryon Oscillation Spectroscopic Survey (BOSS). We restrict the galaxy-galaxy lensing and multipole power spectrum measurements to the overlapping regions with KiDS, and self-consistently compute the full covariance between the different observables using a large suite of $N$-body simulations. We methodically analyze different combinations of the observables, finding that galaxy-galaxy lensing measurements are particularly useful in improving the constraint on the intrinsic alignment amplitude (by 30%, positive at $3.5\sigma$ in the fiducial data analysis), while the multipole power spectra are useful in tightening the constraints along the lensing degeneracy direction (e.g. factor of two stronger matter density constraint in the fiducial analysis). The fully combined constraint on $S_8 \equiv \sigma_8 \sqrt{\Omega_{\rm m}/0.3} = 0.742 \pm 0.035$, which is an improvement by 20% compared to KiDS alone, corresponds to a $2.6\sigma$ discordance with Planck, and is not significantly affected by fitting to a more conservative set of scales. Given the tightening of the parameter space, we are unable to resolve the discordance with an extended cosmology that is simultaneously favored in a model selection sense, including the sum of neutrino masses, curvature, evolving dark energy, and modified gravity. The complementarity of our observables allows for constraints on modified gravity degrees of freedom that are not simultaneously bounded with either probe alone, and up to a factor of three improvement in the $S_8$ constraint in the extended cosmology compared to KiDS alone.Next Generation Virgo Cluster Survey. XXI. The weak lensing masses of the CFHTLS and NGVS RedGOLD galaxy clusters and calibration of the optical richness
Astrophysical Journal American Astronomical Society 848:2 (2017) 114