Gene machines

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The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp

Authors:

Diego Duchi, Abhishek Mazumder, Anssi M Malinen, Richard H Ebright, Achillefs N Kapanidis
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The displacement of the σ70 finger in initial transcription is highly heterogeneous and promoter-dependent

Authors:

Anna Wanga, Abhishek Mazumdera, Achillefs N Kapanidis
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The formation of the bacterial RNA polymerase–promoter open complex involves a branched pathway

Authors:

Anssi M Malinen, Jacob Bakermans, Emil Aalto-Setälä, Martin Blessing, David LV Bauer, Olena Parilova, Georgiy A Belogurov, David Dulin, Achillefs N Kapanidis
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Tightly regulated, yet flexible, directional switching mechanism of a rotary motor

Authors:

Oshri Afanzar, Diana Di Paolo, Miriam Eisenstein, Kohava Levi, Anne Plochowietz, Achillefs N Kapanidis, Richard Michael Berry, Michael Eisenbach
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Transient DNA binding to gapped DNA substrates links DNA sequence to the single-molecule kinetics of protein-DNA interactions

Authors:

Rebecca Andrews, Horst Steuer, Afaf H El-Sagheer, Abhishek Mazumder, Hafez el Sayyed, Arun Shivalingam, Tom Brown, Achillefs N Kapanidis
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