Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation

Authors:

Karin EJ Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn HM Smith, Ashley CW Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker

Induced Polarization in MD Simulations of the 5HT3 Receptor Channel

Cold Spring Harbor Laboratory 2020.03.01.971853

Authors:

Gianni Klesse, Shanlin Rao, Stephen J Tucker, Mark SP Sansom

Influence of Electronic Polarization on the Binding of Anions to a Chloride-Pumping Rhodopsin

Authors:

Linda X Phan, Victor Cruces Chamorro, Hector Martinez-Seara, Jason Crain, Mark SP Sansom, Stephen J Tucker

Influence of effective polarization on ion and water interactions within a biomimetic nanopore

Authors:

Linda X Phan, Charlotte I Lynch, Jason Crain, Mark SP Sansom, Stephen J Tucker

Structural determinants for GqPCR-mediated inhibition of TASK K2P K+ channels and their dysfunction in disease

Authors:

Thibault RH Jouen-Tachoire, Peter Proks, David Seiferth, Kate Crowther, Philip C Biggin, Thomas Baukrowitz, Marcus Schewe, Stephen J Tucker