Molecular machinery built from DNA

NOBEL SYMPOSIUM 153: NANOSCALE ENERGY CONVERTERS 1519 (2013) 81-82

Authors:

Jonathan Bath, Andrew J Turberfield

Probing GPCR-Gα interactions: A functional study by EM and SPR

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 42 (2013) S172-S172

Authors:

RJ Adamson, TH Sharp, DN Selmi, AD Goddard, RJ Gilbert, AJ Turberfield, A Watts

Small molecule signals that direct the route of a molecular cargo.

Small 8:23 (2012) 3593-3597

Authors:

Richard A Muscat, Jonathan Bath, Andrew J Turberfield

Abstract:

The route taken by a DNA cargo on a branched track can be controlled by the small molecule adenosine using a pair of aptamers that reciprocally block and unblock branches of the track in response to adenosine binding.

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics): Preface

, 2012

Authors:

D Stefanovic, A Turberfield

Sequence-specific synthesis of macromolecules using DNA-templated chemistry.

Chem Commun (Camb) 48:45 (2012) 5614-5616

Authors:

Phillip J Milnes, Mireya L McKee, Jonathan Bath, Lijiang Song, Eugen Stulz, Andrew J Turberfield, Rachel K O'Reilly

Abstract:

Using a strand exchange mechanism we have prepared, by DNA templated chemistry, two 10-mers with defined and tunable monomer sequences. An optimized reaction protocol achieves 85% coupling yield per step, demonstrating that DNA-templated chemistry is a powerful tool for the synthesis of macromolecules with full sequence control.