Professor Achillefs Kapanidis: Publications

A protein biosensor that relies on bending of single DNA molecules.

Chemphyschem 13:4 (2012) 918-922

Authors:

Robert Crawford, Douglas J Kelly, Achillefs N Kapanidis

Abstract:

A "bendy" protein sensor: A DNA-based sensor that uses folded DNA (through DNA kinks) and protein-induced bending to detect DNA-binding proteins is presented. Single-molecule sensing of a transcriptional activator (catabolite activator protein, CAP, which bends its DNA site by 80°) is demonstrated in solution and on surfaces, both in buffers and in cell lysates. The method should allow detection of a wide range of DNA-bending proteins.

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Regime-Changing Hidden Markov Modeling and Statistical Analysis for Complex Single-Molecule Time Series

Biophysical Journal Elsevier 102:3 (2012) 595a-596a

Authors:

Kristofer Gryte, Alistair Wardrope, Geraint Evans, Stephan Uphoff, Ludovic Le Reste, Achillefs N Kapanidis

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Single-Molecule DNA Repair in Live Bacteria

Biophysical Journal Elsevier 102:3 (2012) 14a

Authors:

Stephan Uphoff, Rodrigo Reyes-Lamothe, David J Sherratt, Achillefs N Kapanidis

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Single-Molecule FRET in Living Bacteria

Biophysical Journal Elsevier 102:3 (2012) 234a

Authors:

Robert Crawford, Joseph P Torella, Achillefs N Kapanidis

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Single-Molecule Fluorescence Studies of Site-Specific DNA Recombination

Biophysical Journal Elsevier 102:3 (2012) 283a

Authors:

Justin Pinkney, Pawel Zawadzki, David J Sherratt, Achillefs N Kapanidis

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Professor Achillefs Kapanidis

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A protein biosensor that relies on bending of single DNA molecules.

Authors:

Abstract:

Regime-Changing Hidden Markov Modeling and Statistical Analysis for Complex Single-Molecule Time Series

Authors:

Single-Molecule DNA Repair in Live Bacteria

Authors:

Single-Molecule FRET in Living Bacteria

Authors:

Single-Molecule Fluorescence Studies of Site-Specific DNA Recombination

Authors:

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Professor Achillefs Kapanidis

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A protein biosensor that relies on bending of single DNA molecules.

Authors:

Abstract:

Regime-Changing Hidden Markov Modeling and Statistical Analysis for Complex Single-Molecule Time Series

Authors:

Single-Molecule DNA Repair in Live Bacteria

Authors:

Single-Molecule FRET in Living Bacteria

Authors:

Single-Molecule Fluorescence Studies of Site-Specific DNA Recombination

Authors: