Oxford Molecular Motors

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Chemistry: Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication

Science 310:5754 (2005) 1661-1665

Authors:

RP Goodman, IAT Schaap, CF Tardin, CM Erben, RM Berry, CF Schmidt, AJ Turberfield

Abstract:

Practical components for three-dimensional molecular nanofabrication must be simple to produce, stereopure, rigid, and adaptable. We report a family of DNA tetrahedra, less than 10 nanometers on a side, that can self-assemble in seconds with near-quantitative yield of one diastereomer. They can be connected by programmable DNA linkers. Their triangulated architecture confers structural stability; by compressing a DNA tetrahedron with an atomic force microscope, we have measured the axial compressibility of DNA and observed the buckling of the double helix under high loads.
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Intracellular sodium concentration of chimera Escherichia coli

FEBS J 272 (2005) 345-346

Authors:

CJ Lo, MC Leake, RM Berry
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Artificial bilayer lipid membranes (BLMs) on-chip for single molecule sensing

Proceedings of SPIE--the International Society for Optical Engineering SPIE, the international society for optics and photonics 5838 (2005) 252-257

Authors:

Mairi E Sandison, Daniele Malleo, David Holmes, Richard Berry, Hywel Morgan
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ATP synthesis: the world's smallest wind-up toy.

Curr Biol 15:10 (2005) R385-R387

Abstract:

ATP synthase contains two rotary motors coupled back-to-back: the protonmotive force-driven motor F0 pushes the ATP-driven motor F1 in reverse, causing it to synthesize ATP. Half of this process has now been reproduced in vitro, using tiny magnets instead of F0 to drive the reverse rotation of a single F1 molecule.
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E. coli in Motion

Physics Today AIP Publishing 58:2 (2005) 64-65
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