Julia Yeomans OBE FRS

Abstract:

We use continuum simulations to study the impact of friction on the ordering of defects in an active nematic. Even in a frictionless system, +1/2 defects tend to align side by side and orient antiparallel reflecting their propensity to form, and circulate with, flow vortices. Increasing friction enhances the effectiveness of the defect-defect interactions, and defects form dynamically evolving, large-scale, positionally, and orientationally ordered structures, which can be explained as a competition between hexagonal packing, preferred by the −1/2 defects, and rectangular packing, preferred by the +1/2 defects.

Abstract:

We use active nematohydrodynamics to study the flow of an active fluid in a 3D microchannel, finding a transition between active turbulence and regimes where there is a net flow along the channel. We show that the net flow is only possible if the active nematic is flow aligning and that, in agreement with experiments, the appearance of the net flow depends on the aspect ratio of the channel cross section. We explain our results in terms of when the hydrodynamic screening due to the channel walls allows the emergence of vortex rolls across the channel.

Abstract:

Collective chemotaxis plays a key role in the navigation of cell clusters in e.g. embryogenesis and cancer metastasis. Using the active nematic continuum equations, coupled to a chemical field that regulates activity, we demonstrate and explain a physical mechanism that results in collective chemotaxis. The activity naturally leads to cell polarisation at the cluster interface which induces outwards flows. The chemical gradient then breaks the symmetry of the flow field, leading to a net motion. The velocity is independent of the cluster size in agreement with experiment.