Oxford Centre for High Energy Density Science (OxCHEDS)

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High power laser production of short-lived isotopes for positron emission tomography

Journal of Physics D: Applied Physics 37:16 (2004) 2341-2345

Authors:

KWD Ledingham, P McKenna, T McCanny, S Shimizu, JM Yang, L Robson, J Zweit, JM Gillies, J Bailey, GN Chimon, RJ Clarke, D Neely, PA Norreys, JL Collier, RP Singhal, MS Wei, SPD Mangles, P Nilson, K Krushelnick, M Zepf

Abstract:

Positron emission tomography (PET) is a powerful diagnostic/imaging technique requiring the production of the short-lived positron emitting isotopes 11C, 13N, 15O and 18F by proton irradiation of natural/enriched targets using cyclotrons. The development of PET has been hampered due to the size and shielding requirements of nuclear installations. Recent results show that when an intense laser beam interacts with solid targets, megaelectronvolt (MeV) protons capable of producing PET isotopes are generated. This report describes how to generate intense PET sources of 11C and 18F using a petawatt laser beam. The work describing the laser production of 18F through a (p,n) 18O reaction, and the subsequent synthesis of 2-[18F] is reported for the first time. The potential for developing compact laser technology for this purpose is discussed.
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Electronic conduction in shock-compressed water

Physics of Plasmas AIP Publishing 11:8 (2004) l41-l44

Authors:

PM Celliers, GW Collins, DG Hicks, M Koenig, E Henry, A Benuzzi-Mounaix, D Batani, DK Bradley, LB Da Silva, RJ Wallace, SJ Moon, JH Eggert, KKM Lee, LR Benedetti, R Jeanloz, I Masclet, N Dague, B Marchet, M Rabec Le Gloahec, Ch Reverdin, J Pasley, O Willi, D Neely, C Danson
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Laboratory measurements of 0.7 GG magnetic fields generated during high-intensity laser interactions with dense plasmas

Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 70:2 2 (2004)

Authors:

U Wagner, M Tatarakis, A Gopal, FN Bee, EL Clark, AE Dangor, RG Evans, MG Haines, SPD Mangles, PA Norreys, MS Wei, M Zepf, K Krushelnick

Abstract:

Measurements of ultrahigh magnetic fields produced during intense laser interaction with solids were presented. Polarization measurements of high-order laser harmonics suggest the existence of magnetic field strengths of 0.7±0.1 GG. It was found that denser regions of the plasma can be probed using higher order harmonics. The technique was found to be useful for the measurements of multi-GG level magnetic fields.
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Charge-State Distribution and Doppler Effect in an Expanding Photoionized Plasma

Physical Review Letters American Physical Society (APS) 93:5 (2004) 055002

Authors:

ME Foord, RF Heeter, PAM van Hoof, RS Thoe, JE Bailey, ME Cuneo, H-K Chung, DA Liedahl, KB Fournier, GA Chandler, V Jonauskas, R Kisielius, LP Mix, C Ramsbottom, PT Springer, FP Keenan, SJ Rose, WH Goldstein
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Observation of the parametric two-ion decay instability with thomson scattering.

Phys Rev Lett 93:4 (2004) 045004

Authors:

C Niemann, SH Glenzer, J Knight, L Divol, EA Williams, G Gregori, BI Cohen, C Constantin, DH Froula, DS Montgomery, RP Johnson

Abstract:

We present the first direct experimental observation of the parametric two-ion decay instability of ion-acoustic waves driven by a high intensity (5 x 10(15) W cm(-2)) laser beam in a laser produced high-Z plasma. Using two separate Thomson scattering diagnostics simultaneously, we directly measure the scattering from thermal ion-acoustic fluctuations, the primary ion waves that are driven to large amplitudes by the high intensity beam, and the two-ion decay products. The decay products are shown to be present only where the interaction takes place and their k spectrum is broad.
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