Stochastic sensing of polynucleotides using patterned nanopores

ArXiv 1201.4489 (2012)

Authors:

Jack A Cohen, Abhishek Chaudhuri, Ramin Golestanian

Abstract:

The effect of the microscopic structure of a pore on polymer translocation is studied using Langevin dynamics simulation, and the consequence of introducing patterned stickiness inside the pore is investigated. It is found that the translocation process is extremely sensitive to the detailed structure of such patterns with faster than exponential dependence of translocation times on the stickiness of the pore. The stochastic nature of the translocation process leads to discernable differences between how polymers with different sequences go through specifically patterned pores. This notion is utilized to propose a stochastic sensing protocol for polynucleotides, and it is demonstrated that the method, which would be significantly faster than the existing methods, could be made arbitrarily robust.

Collective behavior of thermally active colloids

Physical Review Letters 108:3 (2012)

Abstract:

Colloids with patchy metal coating under laser irradiation could act as local heat sources and generate temperature gradients that could induce self-propulsion and interactions between them. The collective behavior of a dilute solution of such thermally active particles is studied using a stochastic formulation. It is found that when the Soret coefficient is positive, the system could be described in a stationary state by the nonlinear Poisson-Boltzmann equation and could adopt density profiles with significant depletion in the middle region when confined. For colloids with a negative Soret coefficient, the system can be described as a dissipative equivalent of a gravitational system. It is shown that in this case the thermally active colloidal solution could undergo an instability at a critical laser intensity, which has similarities to a supernova explosion. © 2012 American Physical Society.

Extracting short-ranged interactions from structure factors

(2012)

How Peclet number affects microstructure and transient cluster aggregation in sedimenting colloidal suspensions

(2012)

Authors:

A Moncho-Jorda', AA Louis, JT Padding

Phase transitions in topological lattice models via topological symmetry breaking

New Journal of Physics 14 (2012)

Authors:

FJ Burnell, SH Simon, JK Slingerland

Abstract:

We study transitions between phases of matter with topological order. By studying these transitions in exactly solvable lattice models we show how universality classes may be identified and critical properties described. As a familiar example to elucidate our results concretely, we describe in detail a transition between a fully gapped achiral 2D p-wave superconductor (p + ip for pseudo-spin up/p - ip for pseudo-spin down) to an s-wave superconductor. We show in particular that this transition is of the 2D transverse field Ising universality class. © IOP Publishing Ltd and Deutsche Physikalische Gesellschaft.