Condensed Matter Theory

Abstract:

Reducing the contact time between bouncing droplets and an underlying solid surface is relevant to a broad range of industrial applications, such as anti-icing and self-cleaning. Previous work has found that placing cylindrical obstacles on the substrate leads to a reduction in contact time. For obstacles large compared to the drop, this is a result of hydrodynamic coupling between the azimuthal and axial spreading directions. For obstacles small compared to the drop, the reduction in contact time is interpreted as being due to fast retraction along the cylindrical ridge, followed by drop breakup. Here we use simulations to discuss in greater detail the effect of varying the obstacle size on the dynamics of the drop bouncing. We investigate the crossover between the two regimes and explain why the contact time is minimized when the radii of the drop and the cylindrical obstacle are comparable.

Abstract:

Recent experiments have revealed that the diffusivity of exothermic and fast enzymes is enhanced when they are catalytically active, and different physical mechanisms have been explored and quantified to account for this observation. We perform measurements on the endothermic and relatively slow enzyme aldolase, which also shows substrate-induced enhanced diffusion. We propose a new physical paradigm, which reveals that the diffusion coefficient of a model enzyme hydrodynamically coupled to its environment increases significantly when undergoing changes in conformational fluctuations in a substrate concentration dependent manner, and is independent of the overall turnover rate of the underlying enzymatic reaction. Our results show that substrate-induced enhanced diffusion of enzyme molecules can be explained within an equilibrium picture and that the exothermicity of the catalyzed reaction is not a necessary condition for the observation of this phenomenon.